Flumazenil-induced ballism.

Flumazenil, an imidazobenzodiazepine, is the first benzodiazepine antagonist and is being used to reverse the adverse pharmacological effects of benzodiazepine. There have been a few reports on the central nevous system side effects with its use. We report a patient with generalized ballism followin...

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Autores principales: Kim, Joong-Seok, Ko, Seok-Bum, Choi, Yeong-Bin, Lee, Kwang-Soo
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055007/
https://www.ncbi.nlm.nih.gov/pubmed/12692435
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author Kim, Joong-Seok
Ko, Seok-Bum
Choi, Yeong-Bin
Lee, Kwang-Soo
author_facet Kim, Joong-Seok
Ko, Seok-Bum
Choi, Yeong-Bin
Lee, Kwang-Soo
author_sort Kim, Joong-Seok
collection PubMed
description Flumazenil, an imidazobenzodiazepine, is the first benzodiazepine antagonist and is being used to reverse the adverse pharmacological effects of benzodiazepine. There have been a few reports on the central nevous system side effects with its use. We report a patient with generalized ballism following administration of flumazenil. The mechanism through which flumazenil induced this symptom is unknown. It is conceivable that flumazenil may antagonize the GABA-benzodiazepine receptor complex and induce dopamine hypersensitivity, thus induce dyskinesic symptoms.
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spelling pubmed-30550072011-03-15 Flumazenil-induced ballism. Kim, Joong-Seok Ko, Seok-Bum Choi, Yeong-Bin Lee, Kwang-Soo J Korean Med Sci Research Article Flumazenil, an imidazobenzodiazepine, is the first benzodiazepine antagonist and is being used to reverse the adverse pharmacological effects of benzodiazepine. There have been a few reports on the central nevous system side effects with its use. We report a patient with generalized ballism following administration of flumazenil. The mechanism through which flumazenil induced this symptom is unknown. It is conceivable that flumazenil may antagonize the GABA-benzodiazepine receptor complex and induce dopamine hypersensitivity, thus induce dyskinesic symptoms. Korean Academy of Medical Sciences 2003-04 /pmc/articles/PMC3055007/ /pubmed/12692435 Text en
spellingShingle Research Article
Kim, Joong-Seok
Ko, Seok-Bum
Choi, Yeong-Bin
Lee, Kwang-Soo
Flumazenil-induced ballism.
title Flumazenil-induced ballism.
title_full Flumazenil-induced ballism.
title_fullStr Flumazenil-induced ballism.
title_full_unstemmed Flumazenil-induced ballism.
title_short Flumazenil-induced ballism.
title_sort flumazenil-induced ballism.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055007/
https://www.ncbi.nlm.nih.gov/pubmed/12692435
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AT choiyeongbin flumazenilinducedballism
AT leekwangsoo flumazenilinducedballism

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