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Localized amyloidosis of seminal vesicle and vas deferens: report of two cases.

We reported localized amyloidosis involving seminal vesicles and vasa deferentia, which was found in two patients with prostatic adenocarcinoma. A 60-yr-old (Case 1) and a 59-yr-old (Case 2) man came to our hospital with elevation of serum prostate-specific antigen (PSA) and biopsy proven carcinoma,...

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Autores principales: Jun, Sun-Young, Kim, Kyu-Rae, Cho, Kyoung-Sik, Ro, Jae Y.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055036/
https://www.ncbi.nlm.nih.gov/pubmed/12808339
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author Jun, Sun-Young
Kim, Kyu-Rae
Cho, Kyoung-Sik
Ro, Jae Y.
author_facet Jun, Sun-Young
Kim, Kyu-Rae
Cho, Kyoung-Sik
Ro, Jae Y.
author_sort Jun, Sun-Young
collection PubMed
description We reported localized amyloidosis involving seminal vesicles and vasa deferentia, which was found in two patients with prostatic adenocarcinoma. A 60-yr-old (Case 1) and a 59-yr-old (Case 2) man came to our hospital with elevation of serum prostate-specific antigen (PSA) and biopsy proven carcinoma, respectively. MRI revealed multiple irregular foci of low signal intensity in the prostates as well as in both seminal vesicles and vasa deferentia on T2-weighted imaging, suggesting prostatic carcinoma with extension to both seminal vesicles and vasa deferentia in both cases. Under the clinical diagnosis of stage III prostatic adenocarcinoma, a radical prostatectomy was performed in both patients. Microscopically, Gleason score 7 adenocarcinoma was observed in both patients. In addition, isolated amyloidosis of both seminal vesicles and vasa deferentia was found without carcinoma involvement. Localized amyloidosis in the seminal vesicles, which is considered as senile process, has been occasionally reported in the autopsy and in the surgical specimens. Amyloid deposition in the vas deferens has also been reported in the literature, however, the deposition mimicking extension of carcinoma has not been reported. In this report, two cases of isolated amyloidosis of the seminal vesicles and vasa deferentia are described with electron microscopic study and literature review.
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spelling pubmed-30550362011-03-15 Localized amyloidosis of seminal vesicle and vas deferens: report of two cases. Jun, Sun-Young Kim, Kyu-Rae Cho, Kyoung-Sik Ro, Jae Y. J Korean Med Sci Research Article We reported localized amyloidosis involving seminal vesicles and vasa deferentia, which was found in two patients with prostatic adenocarcinoma. A 60-yr-old (Case 1) and a 59-yr-old (Case 2) man came to our hospital with elevation of serum prostate-specific antigen (PSA) and biopsy proven carcinoma, respectively. MRI revealed multiple irregular foci of low signal intensity in the prostates as well as in both seminal vesicles and vasa deferentia on T2-weighted imaging, suggesting prostatic carcinoma with extension to both seminal vesicles and vasa deferentia in both cases. Under the clinical diagnosis of stage III prostatic adenocarcinoma, a radical prostatectomy was performed in both patients. Microscopically, Gleason score 7 adenocarcinoma was observed in both patients. In addition, isolated amyloidosis of both seminal vesicles and vasa deferentia was found without carcinoma involvement. Localized amyloidosis in the seminal vesicles, which is considered as senile process, has been occasionally reported in the autopsy and in the surgical specimens. Amyloid deposition in the vas deferens has also been reported in the literature, however, the deposition mimicking extension of carcinoma has not been reported. In this report, two cases of isolated amyloidosis of the seminal vesicles and vasa deferentia are described with electron microscopic study and literature review. Korean Academy of Medical Sciences 2003-06 /pmc/articles/PMC3055036/ /pubmed/12808339 Text en
spellingShingle Research Article
Jun, Sun-Young
Kim, Kyu-Rae
Cho, Kyoung-Sik
Ro, Jae Y.
Localized amyloidosis of seminal vesicle and vas deferens: report of two cases.
title Localized amyloidosis of seminal vesicle and vas deferens: report of two cases.
title_full Localized amyloidosis of seminal vesicle and vas deferens: report of two cases.
title_fullStr Localized amyloidosis of seminal vesicle and vas deferens: report of two cases.
title_full_unstemmed Localized amyloidosis of seminal vesicle and vas deferens: report of two cases.
title_short Localized amyloidosis of seminal vesicle and vas deferens: report of two cases.
title_sort localized amyloidosis of seminal vesicle and vas deferens: report of two cases.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055036/
https://www.ncbi.nlm.nih.gov/pubmed/12808339
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