Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS.

In a patient receiving 5-fluorouracil and levamisole, neurologic deficits suggest the cerebral demyelinating syndrome as a differential diagnosis. The authors report a patient diagnosed as multifocal inflammatory leukoencephalopathy for which thallium-201 (201Tl) single photon emission computed tomo...

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Detalles Bibliográficos
Autores principales: Hwang, Yang Ha, Suh, Chung Kyu, Park, Sung Pa
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055079/
https://www.ncbi.nlm.nih.gov/pubmed/12923348
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author Hwang, Yang Ha
Suh, Chung Kyu
Park, Sung Pa
author_facet Hwang, Yang Ha
Suh, Chung Kyu
Park, Sung Pa
author_sort Hwang, Yang Ha
collection PubMed
description In a patient receiving 5-fluorouracil and levamisole, neurologic deficits suggest the cerebral demyelinating syndrome as a differential diagnosis. The authors report a patient diagnosed as multifocal inflammatory leukoencephalopathy for which thallium-201 (201Tl) single photon emission computed tomography (SPECT) and proton magnetic resonance spectroscopy (MRS) were employed as noninvasive diagnostic tools. 201Tl SPECT study was negative and proton MRS showed an increase of choline and lactate and well preserved N-acetylaspartate. These findings support histopathologic findings of multifocal inflammatory leukoencephalopathy revealing demyelination with relative axonal sparing in the patient.
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spelling pubmed-30550792011-03-15 Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS. Hwang, Yang Ha Suh, Chung Kyu Park, Sung Pa J Korean Med Sci Research Article In a patient receiving 5-fluorouracil and levamisole, neurologic deficits suggest the cerebral demyelinating syndrome as a differential diagnosis. The authors report a patient diagnosed as multifocal inflammatory leukoencephalopathy for which thallium-201 (201Tl) single photon emission computed tomography (SPECT) and proton magnetic resonance spectroscopy (MRS) were employed as noninvasive diagnostic tools. 201Tl SPECT study was negative and proton MRS showed an increase of choline and lactate and well preserved N-acetylaspartate. These findings support histopathologic findings of multifocal inflammatory leukoencephalopathy revealing demyelination with relative axonal sparing in the patient. Korean Academy of Medical Sciences 2003-08 /pmc/articles/PMC3055079/ /pubmed/12923348 Text en
spellingShingle Research Article
Hwang, Yang Ha
Suh, Chung Kyu
Park, Sung Pa
Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS.
title Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS.
title_full Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS.
title_fullStr Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS.
title_full_unstemmed Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS.
title_short Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS.
title_sort multifocal inflammatory leukoencephalopathy: use of thallium-201 spect and proton mrs.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055079/
https://www.ncbi.nlm.nih.gov/pubmed/12923348
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AT suhchungkyu multifocalinflammatoryleukoencephalopathyuseofthallium201spectandprotonmrs
AT parksungpa multifocalinflammatoryleukoencephalopathyuseofthallium201spectandprotonmrs

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