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CARBANA: Carbon analysis program forprotein sequences
There are lots of works gone into proteins to understand the nature of proteins. Hydrophobic interaction is the dominant force that drives the proteins to carry out the biochemical reactions in all living system. Carbon is the only element that contributes towards this hydrophobic interaction. Studi...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Biomedical Informatics
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055155/ https://www.ncbi.nlm.nih.gov/pubmed/21423892 |
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author | Rajasekaran, Ekambaram Vijayasarathy, Marimuthu |
author_facet | Rajasekaran, Ekambaram Vijayasarathy, Marimuthu |
author_sort | Rajasekaran, Ekambaram |
collection | PubMed |
description | There are lots of works gone into proteins to understand the nature of proteins. Hydrophobic interaction is the dominant force that drives the proteins to carry out the biochemical reactions in all living system. Carbon is the only element that contributes towards this hydrophobic interaction. Studies find that globular proteins prefer to have 31.45% of carbon for its stability. Taking this as standard, a carbon analysis program has been developed to study the carbon distribution profile of protein sequences. This carbon analysis program has been made available online. This can be accessed at www.rajasekaran.net.in/tools/carbana.html. This new program is hoped to help in identification and development of active sites, study of protein stability, evolutionary understating of proteins, gene identification, ligand binding site identification, and to solve the long-standing problem of protein-protein and protein-DNA interactions. |
format | Text |
id | pubmed-3055155 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-30551552011-03-18 CARBANA: Carbon analysis program forprotein sequences Rajasekaran, Ekambaram Vijayasarathy, Marimuthu Bioinformation Software There are lots of works gone into proteins to understand the nature of proteins. Hydrophobic interaction is the dominant force that drives the proteins to carry out the biochemical reactions in all living system. Carbon is the only element that contributes towards this hydrophobic interaction. Studies find that globular proteins prefer to have 31.45% of carbon for its stability. Taking this as standard, a carbon analysis program has been developed to study the carbon distribution profile of protein sequences. This carbon analysis program has been made available online. This can be accessed at www.rajasekaran.net.in/tools/carbana.html. This new program is hoped to help in identification and development of active sites, study of protein stability, evolutionary understating of proteins, gene identification, ligand binding site identification, and to solve the long-standing problem of protein-protein and protein-DNA interactions. Biomedical Informatics 2011-02-15 /pmc/articles/PMC3055155/ /pubmed/21423892 Text en © 2011 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited. |
spellingShingle | Software Rajasekaran, Ekambaram Vijayasarathy, Marimuthu CARBANA: Carbon analysis program forprotein sequences |
title | CARBANA: Carbon analysis program forprotein sequences |
title_full | CARBANA: Carbon analysis program forprotein sequences |
title_fullStr | CARBANA: Carbon analysis program forprotein sequences |
title_full_unstemmed | CARBANA: Carbon analysis program forprotein sequences |
title_short | CARBANA: Carbon analysis program forprotein sequences |
title_sort | carbana: carbon analysis program forprotein sequences |
topic | Software |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055155/ https://www.ncbi.nlm.nih.gov/pubmed/21423892 |
work_keys_str_mv | AT rajasekaranekambaram carbanacarbonanalysisprogramforproteinsequences AT vijayasarathymarimuthu carbanacarbonanalysisprogramforproteinsequences |