Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis

BACKGROUND: Autotaxin (ATX) is a secreted glycoprotein with the lysophospholipase D (lysoPLD) activity to convert lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), a bioactive lysophospholipid involved in diverse biological actions. ATX is highly expressed in some cancer cells and cont...

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Detalles Bibliográficos
Autores principales: Li, Song, Wang, Baolu, Xu, Yan, Zhang, Junjie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055229/
https://www.ncbi.nlm.nih.gov/pubmed/21314984
http://dx.doi.org/10.1186/1476-4598-10-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055229/
https://www.ncbi.nlm.nih.gov/pubmed/21314984
http://dx.doi.org/10.1186/1476-4598-10-18

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