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The PTPN22*C1858T functional polymorphism is associated with susceptibility to inflammatory polyarthritis but neither this nor other variants spanning the gene is associated with disease outcome
BACKGROUND: The PTPN22 gene has been widely confirmed as a susceptibility gene for rheumatoid arthritis (RA) in populations of Northern European descent. The aim of the current study was to explore the role of variants spanning the PTPN22 gene in determining susceptibility to and outcome of inflamma...
Autores principales: | Naseem, H, Thomson, W, Silman, A, Worthington, J, Symmons, D, Barton, A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055597/ https://www.ncbi.nlm.nih.gov/pubmed/17666450 http://dx.doi.org/10.1136/ard.2007.071894 |
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