Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?

Osteonecrosis after craniofacial radiation (ORN), osteomyelitis and bisphosphonates related necrosis of the jaw (BRONJ) are the predominant bone diseases in Cranio- and Maxillofacial surgery. Although various hypothesis for the pathophysiological mechanisms including infection, altered vascularisati...

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Detalles Bibliográficos
Autores principales: Handschel, Jörg, Meyer, Ulrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055822/
https://www.ncbi.nlm.nih.gov/pubmed/21332971
http://dx.doi.org/10.1186/1746-160X-7-5
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author Handschel, Jörg
Meyer, Ulrich
author_facet Handschel, Jörg
Meyer, Ulrich
author_sort Handschel, Jörg
collection PubMed
description Osteonecrosis after craniofacial radiation (ORN), osteomyelitis and bisphosphonates related necrosis of the jaw (BRONJ) are the predominant bone diseases in Cranio- and Maxillofacial surgery. Although various hypothesis for the pathophysiological mechanisms including infection, altered vascularisation or remodelling exist, the treatment is still a challenge for clinicians. As the classical pharmacological or surgical treatment protocols have only limited success, stem cells might be a promising treatment option, indicated by recently published data.
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spelling pubmed-30558222011-03-12 Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws? Handschel, Jörg Meyer, Ulrich Head Face Med Editorial Osteonecrosis after craniofacial radiation (ORN), osteomyelitis and bisphosphonates related necrosis of the jaw (BRONJ) are the predominant bone diseases in Cranio- and Maxillofacial surgery. Although various hypothesis for the pathophysiological mechanisms including infection, altered vascularisation or remodelling exist, the treatment is still a challenge for clinicians. As the classical pharmacological or surgical treatment protocols have only limited success, stem cells might be a promising treatment option, indicated by recently published data. BioMed Central 2011-02-18 /pmc/articles/PMC3055822/ /pubmed/21332971 http://dx.doi.org/10.1186/1746-160X-7-5 Text en Copyright ©2011 Handschel and Meyer; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Editorial
Handschel, Jörg
Meyer, Ulrich
Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?
title Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?
title_full Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?
title_fullStr Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?
title_full_unstemmed Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?
title_short Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?
title_sort infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055822/
https://www.ncbi.nlm.nih.gov/pubmed/21332971
http://dx.doi.org/10.1186/1746-160X-7-5
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