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Effect of Xpcl1 Activation and p27(Kip1) Loss on Gene Expression in Murine Lymphoma

Mice lacking the p27(Kip1) Cdk inhibitor (Cdkn1b) exhibit increased susceptibility to lymphomas from the Maloney murine leukemia virus (M-MuLV), and exhibit a high frequency of viral integrations at Xpcl1 (Kis2), a locus on the X-chromosome. Xpcl1 encodes miR-106a∼363, a cluster of microRNAs that ar...

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Detalles Bibliográficos
Autores principales:	Kuppers, Daniel A., Hwang, Harry C., Jackson, Aimee L., Linsley, Peter S., Clurman, Bruce E., Fero, Matthew L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055866/ https://www.ncbi.nlm.nih.gov/pubmed/21412408 http://dx.doi.org/10.1371/journal.pone.0014758

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