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Palmitate-induced skeletal muscle insulin resistance does not require NF-κB activation
Palmitate activates the NF-κB pathway, and induces accumulation of lipid metabolites and insulin resistance in skeletal muscle cells. Little information is available whether and how these processes are causally related. Therefore, the objectives were to investigate whether intra-cellular lipid metab...
Autores principales: | Hommelberg, Pascal P. H., Plat, Jogchum, Sparks, Lauren M., Schols, Annemie M. W. J., van Essen, Anon L. M., Kelders, Marco C. J. M., van Beurden, Denis, Mensink, Ronald P., Langen, Ramon C. J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SP Birkhäuser Verlag Basel
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056136/ https://www.ncbi.nlm.nih.gov/pubmed/20820848 http://dx.doi.org/10.1007/s00018-010-0515-3 |
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