Genetic Etiology of Parkinson Disease Associated with Mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 Genes: A Mutation Update

To date, molecular genetic analyses have identified over 500 distinct DNA variants in five disease genes associated with familial Parkinson disease; α-synuclein (SNCA), parkin (PARK2), PTEN-induced putative kinase 1 (PINK1), DJ-1 (PARK7), and Leucine-rich repeat kinase 2 (LRRK2). These genetic varia...

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Detalles Bibliográficos
Autores principales: Nuytemans, Karen, Theuns, Jessie, Cruts, Marc, Van Broeckhoven, Christine
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Mutation Update
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056147/
https://www.ncbi.nlm.nih.gov/pubmed/20506312
http://dx.doi.org/10.1002/humu.21277

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