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Regulation of Senescence in Cancer and Aging
Senescence is regarded as a physiological response of cells to stress, including telomere dysfunction, aberrant oncogenic activation, DNA damage, and oxidative stress. This stress response has an antagonistically pleiotropic effect to organisms: beneficial as a tumor suppressor, but detrimental by c...
Autores principales: | Kong, Yahui, Cui, Hang, Ramkumar, Charusheila, Zhang, Hong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056284/ https://www.ncbi.nlm.nih.gov/pubmed/21423549 http://dx.doi.org/10.4061/2011/963172 |
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