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TGF-β Inducible Early Gene 1 Regulates Osteoclast Differentiation and Survival by Mediating the NFATc1, AKT, and MEK/ERK Signaling Pathways

TGF-β Inducible Early Gene-1 (TIEG1) is a Krüppel-like transcription factor (KLF10) that was originally cloned from human osteoblasts as an early response gene to TGF-β treatment. As reported previously, TIEG1(−/−) mice have decreased cortical bone thickness and vertebral bone volume and have increa...

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Detalles Bibliográficos
Autores principales:	Cicek, Muzaffer, Vrabel, Anne, Sturchio, Catherine, Pederson, Larry, Hawse, John R., Subramaniam, Malayannan, Spelsberg, Thomas C., Oursler, Merry Jo
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056664/ https://www.ncbi.nlm.nih.gov/pubmed/21423731 http://dx.doi.org/10.1371/journal.pone.0017522

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