Carcinoma-Derived Interleukin-8 Disorients Dendritic Cell Migration Without Impairing T-Cell Stimulation

BACKGROUND: Interleukin-8 (IL-8, CXCL8) is readily produced by human malignant cells. Dendritic cells (DC) both produce IL-8 and express the IL-8 functional receptors CXCR1 and CXCR2. Most human colon carcinomas produce IL-8. IL-8 importance in malignancies has been ascribed to angiogeneis promotion...

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Detalles Bibliográficos
Autores principales: Alfaro, Carlos, Suárez, Natalia, Martínez-Forero, Ivan, Palazón, Asís, Rouzaut, Ana, Solano, Sarai, Feijoo, Esperanza, Gúrpide, Alfonso, Bolaños, Elixabet, Erro, Lorena, Dubrot, Juan, Hervás-Stubbs, Sandra, Gonzalez, Alvaro, Perez-Gracia, Jose Luis, Melero, Ignacio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056721/
https://www.ncbi.nlm.nih.gov/pubmed/21423807
http://dx.doi.org/10.1371/journal.pone.0017922

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