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Recent evolution of the NF-κB and inflammasome regulating protein POP2 in primates
BACKGROUND: Pyrin-only protein 2 (POP2) is a small human protein comprised solely of a pyrin domain that inhibits NF-κB p65/RelA and blocks the formation of functional IL-1β processing inflammasomes. Pyrin proteins are abundant in mammals and several, like POP2, have been linked to activation or reg...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056782/ https://www.ncbi.nlm.nih.gov/pubmed/21362197 http://dx.doi.org/10.1186/1471-2148-11-56 |