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Recent evolution of the NF-κB and inflammasome regulating protein POP2 in primates

BACKGROUND: Pyrin-only protein 2 (POP2) is a small human protein comprised solely of a pyrin domain that inhibits NF-κB p65/RelA and blocks the formation of functional IL-1β processing inflammasomes. Pyrin proteins are abundant in mammals and several, like POP2, have been linked to activation or reg...

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Detalles Bibliográficos
Autores principales:	Atianand, Maninjay K, Fuchs, Travis, Harton, Jonathan A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056782/ https://www.ncbi.nlm.nih.gov/pubmed/21362197 http://dx.doi.org/10.1186/1471-2148-11-56

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