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A Critical Role for Neurofascin in Regulating Action Potential Initiation through Maintenance of the Axon Initial Segment
The axon initial segment (AIS) is critical for the initiation and propagation of action potentials. Assembly of the AIS requires interactions between scaffolding molecules and voltage-gated sodium channels, but the molecular mechanisms that stabilize the AIS are poorly understood. The neuronal isofo...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057015/ https://www.ncbi.nlm.nih.gov/pubmed/21382554 http://dx.doi.org/10.1016/j.neuron.2011.02.021 |