A Critical Role for Neurofascin in Regulating Action Potential Initiation through Maintenance of the Axon Initial Segment

The axon initial segment (AIS) is critical for the initiation and propagation of action potentials. Assembly of the AIS requires interactions between scaffolding molecules and voltage-gated sodium channels, but the molecular mechanisms that stabilize the AIS are poorly understood. The neuronal isofo...

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Detalles Bibliográficos
Autores principales: Zonta, Barbara, Desmazieres, Anne, Rinaldi, Arianna, Tait, Steven, Sherman, Diane L., Nolan, Matthew F., Brophy, Peter J.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057015/
https://www.ncbi.nlm.nih.gov/pubmed/21382554
http://dx.doi.org/10.1016/j.neuron.2011.02.021

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