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Autotaxin: Its Role in Biology of Melanoma Cells and as a Pharmacological Target
Autotaxin (ATX) is an extracellular lysophospholipase D (lysoPLD) released from normal cells and cancer cells. Activity of ATX is detected in various biological fluids. The lysophosphatidic acid (LPA) is the main product of ATX. LPA acting through specific G protein-coupled receptors (LPA(1)-LPA(6))...
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| Formato: | Texto |
| Lenguaje: | English |
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SAGE-Hindawi Access to Research
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057024/ https://www.ncbi.nlm.nih.gov/pubmed/21423677 http://dx.doi.org/10.4061/2011/194857 |