Beneficial Regulation of Matrix Metalloproteinases for Skin Health

Matrix metalloproteinases (MMPs) are essential to the remodeling of the extracellular matrix. While their upregulation facilitates aging and cancer, they are essential to epidermal differentiation and the prevention of wound scars. The pharmaceutical industry is active in identifying products that i...

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Detalles Bibliográficos
Autores principales: Philips, Neena, Auler, Susan, Hugo, Raul, Gonzalez, Salvador
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057026/
https://www.ncbi.nlm.nih.gov/pubmed/21423679
http://dx.doi.org/10.4061/2011/427285
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author Philips, Neena
Auler, Susan
Hugo, Raul
Gonzalez, Salvador
author_facet Philips, Neena
Auler, Susan
Hugo, Raul
Gonzalez, Salvador
author_sort Philips, Neena
collection PubMed
description Matrix metalloproteinases (MMPs) are essential to the remodeling of the extracellular matrix. While their upregulation facilitates aging and cancer, they are essential to epidermal differentiation and the prevention of wound scars. The pharmaceutical industry is active in identifying products that inhibit MMPs to prevent or treat aging and cancer and products that stimulate MMPs to prevent epidermal hyperproliferative diseases and wound scars.
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spelling pubmed-30570262011-03-21 Beneficial Regulation of Matrix Metalloproteinases for Skin Health Philips, Neena Auler, Susan Hugo, Raul Gonzalez, Salvador Enzyme Res Review Article Matrix metalloproteinases (MMPs) are essential to the remodeling of the extracellular matrix. While their upregulation facilitates aging and cancer, they are essential to epidermal differentiation and the prevention of wound scars. The pharmaceutical industry is active in identifying products that inhibit MMPs to prevent or treat aging and cancer and products that stimulate MMPs to prevent epidermal hyperproliferative diseases and wound scars. SAGE-Hindawi Access to Research 2011-03-08 /pmc/articles/PMC3057026/ /pubmed/21423679 http://dx.doi.org/10.4061/2011/427285 Text en Copyright © 2011 Neena Philips et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Philips, Neena
Auler, Susan
Hugo, Raul
Gonzalez, Salvador
Beneficial Regulation of Matrix Metalloproteinases for Skin Health
title Beneficial Regulation of Matrix Metalloproteinases for Skin Health
title_full Beneficial Regulation of Matrix Metalloproteinases for Skin Health
title_fullStr Beneficial Regulation of Matrix Metalloproteinases for Skin Health
title_full_unstemmed Beneficial Regulation of Matrix Metalloproteinases for Skin Health
title_short Beneficial Regulation of Matrix Metalloproteinases for Skin Health
title_sort beneficial regulation of matrix metalloproteinases for skin health
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057026/
https://www.ncbi.nlm.nih.gov/pubmed/21423679
http://dx.doi.org/10.4061/2011/427285
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