CENP-B preserves genome integrity at replication forks paused by Retrotransposon LTR

Centromere-binding protein B (CENP-B) is a widely conserved DNA binding factor associated with heterochromatin and centromeric satellite repeats1. In fission yeast, CENP-B homologs have been shown to silence Long Terminal Repeat (LTR) retrotransposons by recruiting histone deacetylases2. However, CE...

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Detalles Bibliográficos
Autores principales: Zaratiegui, Mikel, Vaughn, Matthew W., Irvine, Danielle V., Goto, Derek, Watt, Stephen, Bähler, Jürg, Arcangioli, Benoit, Martienssen, Robert A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057531/
https://www.ncbi.nlm.nih.gov/pubmed/21151105
http://dx.doi.org/10.1038/nature09608

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