The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

Cancer is a disease consisting of both genetic and epigenetic changes. While increasing evidence demonstrates that tumour progression entails chromatin-mediated changes such as DNA methylation, the role of histone variants in cancer initiation and progression currently remains unclear. Here, we repo...

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Detalles Bibliográficos
Autores principales: Kapoor, Avnish, Goldberg, Matthew S., Cumberland, Lara K., Ratnakumar, Kajan, Segura, Miguel F., Emanuel, Patrick O., Menendez, Silvia, Vardabasso, Chiara, LeRoy, Gary, Vidal, Claudia I., Polsky, David, Osman, Iman, Garcia, Benjamin A., Hernando, Eva, Bernstein, Emily
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057940/
https://www.ncbi.nlm.nih.gov/pubmed/21179167
http://dx.doi.org/10.1038/nature09590

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