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TACE/ADAM-17 Phosphorylation by PKC-Epsilon Mediates Premalignant Changes in Tobacco Smoke-Exposed Lung Cells

BACKGROUND: Tobacco smoke predisposes humans and animals to develop lung tumors, but the molecular events responsible for this are poorly understood. We recently showed that signaling mechanisms triggered by smoke in lung cells could lead to the activation of a growth factor signaling pathway, there...

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Detalles Bibliográficos
Autores principales: Lemjabbar-Alaoui, Hassan, Sidhu, Sukhvinder S., Mengistab, Aklilu, Gallup, Marianne, Basbaum, Carol
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057966/
https://www.ncbi.nlm.nih.gov/pubmed/21423656
http://dx.doi.org/10.1371/journal.pone.0017489

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