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Identification of CD4(+) T Cell Epitopes in C. burnetii Antigens Targeted by Antibody Responses

Coxiella burnetii is an obligate intracellular Gram-negative bacterium that causes acute Q fever and chronic infections in humans. A killed, whole cell vaccine is efficacious, but vaccination can result in severe local or systemic adverse reactions. Although T cell responses are considered pivotal f...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Dow, Courtney, Wang, Peng, Sidney, John, Read, Amanda, Harmsen, Allen, Samuel, James E., Peters, Bjoern
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057979/
https://www.ncbi.nlm.nih.gov/pubmed/21423609
http://dx.doi.org/10.1371/journal.pone.0017712