X-Ray Structure of the Human Calreticulin Globular Domain Reveals a Peptide-Binding Area and Suggests a Multi-Molecular Mechanism

In the endoplasmic reticulum, calreticulin acts as a chaperone and a Ca(2+)-signalling protein. At the cell surface, it mediates numerous important biological effects. The crystal structure of the human calreticulin globular domain was solved at 1.55 Å resolution. Interactions of the flexible N-term...

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Detalles Bibliográficos
Autores principales: Chouquet, Anne, Païdassi, Helena, Ling, Wai Li, Frachet, Philippe, Houen, Gunnar, Arlaud, Gérard J., Gaboriaud, Christine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057994/
https://www.ncbi.nlm.nih.gov/pubmed/21423620
http://dx.doi.org/10.1371/journal.pone.0017886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057994/
https://www.ncbi.nlm.nih.gov/pubmed/21423620
http://dx.doi.org/10.1371/journal.pone.0017886

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