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Potent Anti-Tumor Effect Generated by a Novel Human Papillomavirus (HPV) Antagonist Peptide Reactivating the pRb/E2F Pathway

Human papillomavirus type 16 (HPV16) E7 is a viral oncoprotein believed to play a major role in cervical cancer. In this study, an antagonist peptide against HPV16E7 protein was first identified from screening the c7c phage display peptide library. The binding specificity and affinity of the selecte...

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Detalles Bibliográficos
Autores principales:	Guo, Cai-ping, Liu, Ke-wei, Luo, Hai-bo, Chen, Hong-bo, Zheng, Yi, Sun, Shen-nan, Zhang, Qian, Huang, Laiqiang
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057995/ https://www.ncbi.nlm.nih.gov/pubmed/21423621 http://dx.doi.org/10.1371/journal.pone.0017734

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