Cargando…

Cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective

This paper reviews the current literature on smoke inhalation injuries with special attention to the effects of hydrogen cyanide. It is assumed that cyanide poisoning is still an overlooked diagnosis in fire victims. Treatment against cyanide poisoning in the emergency setting should be given based...

Descripción completa

Detalles Bibliográficos
Autores principales: Lawson-Smith, Pia, Jansen, Erik C, Hyldegaard, Ole
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058018/
https://www.ncbi.nlm.nih.gov/pubmed/21371322
http://dx.doi.org/10.1186/1757-7241-19-14
_version_ 1782200325494538240
author Lawson-Smith, Pia
Jansen, Erik C
Hyldegaard, Ole
author_facet Lawson-Smith, Pia
Jansen, Erik C
Hyldegaard, Ole
author_sort Lawson-Smith, Pia
collection PubMed
description This paper reviews the current literature on smoke inhalation injuries with special attention to the effects of hydrogen cyanide. It is assumed that cyanide poisoning is still an overlooked diagnosis in fire victims. Treatment against cyanide poisoning in the emergency setting should be given based on the clinical diagnosis only. Oxygen in combination with a recommended antidote should be given immediately, the first to reduce cellular hypoxia and the second to eliminate cyanide. A specific antidote is hydroxycobalamin, which can be given iv. and has few side effects.
format Text
id pubmed-3058018
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-30580182011-03-16 Cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective Lawson-Smith, Pia Jansen, Erik C Hyldegaard, Ole Scand J Trauma Resusc Emerg Med Review This paper reviews the current literature on smoke inhalation injuries with special attention to the effects of hydrogen cyanide. It is assumed that cyanide poisoning is still an overlooked diagnosis in fire victims. Treatment against cyanide poisoning in the emergency setting should be given based on the clinical diagnosis only. Oxygen in combination with a recommended antidote should be given immediately, the first to reduce cellular hypoxia and the second to eliminate cyanide. A specific antidote is hydroxycobalamin, which can be given iv. and has few side effects. BioMed Central 2011-03-03 /pmc/articles/PMC3058018/ /pubmed/21371322 http://dx.doi.org/10.1186/1757-7241-19-14 Text en Copyright ©2011 Lawson-Smith et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Lawson-Smith, Pia
Jansen, Erik C
Hyldegaard, Ole
Cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective
title Cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective
title_full Cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective
title_fullStr Cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective
title_full_unstemmed Cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective
title_short Cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective
title_sort cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058018/
https://www.ncbi.nlm.nih.gov/pubmed/21371322
http://dx.doi.org/10.1186/1757-7241-19-14
work_keys_str_mv AT lawsonsmithpia cyanideintoxicationaspartofsmokeinhalationareviewondiagnosisandtreatmentfromtheemergencyperspective
AT jansenerikc cyanideintoxicationaspartofsmokeinhalationareviewondiagnosisandtreatmentfromtheemergencyperspective
AT hyldegaardole cyanideintoxicationaspartofsmokeinhalationareviewondiagnosisandtreatmentfromtheemergencyperspective