Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

BACKGROUND: Aneuploidy and chromosomal instability (CIN) are common abnormalities in human cancer. Alterations of the mitotic spindle checkpoint are likely to contribute to these phenotypes, but little is known about somatic alterations of mitotic spindle checkpoint genes in breast cancer. METHODS:...

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Detalles Bibliográficos
Autores principales: Bièche, Ivan, Vacher, Sophie, Lallemand, François, Tozlu-Kara, Sengül, Bennani, Hind, Beuzelin, Michèle, Driouch, Keltouma, Rouleau, Etienne, Lerebours, Florence, Ripoche, Hugues, Cizeron-Clairac, Géraldine, Spyratos, Frédérique, Lidereau, Rosette
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058099/
https://www.ncbi.nlm.nih.gov/pubmed/21352579
http://dx.doi.org/10.1186/1476-4598-10-23

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