Perinatal photoperiod imprints the circadian clock

Using real-time gene expression imaging and behavioral analysis, we found that perinatal photoperiod has lasting effects on the circadian rhythms expressed by clock neurons as well as on mouse behavior, and sets the responsiveness of the biological clock to subsequent changes in photoperiod. These d...

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Detalles Bibliográficos
Autores principales: Ciarleglio, Christopher M, Axley, John C, Strauss, Benjamin R, Gamble, Karen L, McMahon, Douglas G
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058292/
https://www.ncbi.nlm.nih.gov/pubmed/21131951
http://dx.doi.org/10.1038/nn.2699
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author Ciarleglio, Christopher M
Axley, John C
Strauss, Benjamin R
Gamble, Karen L
McMahon, Douglas G
author_facet Ciarleglio, Christopher M
Axley, John C
Strauss, Benjamin R
Gamble, Karen L
McMahon, Douglas G
author_sort Ciarleglio, Christopher M
collection PubMed
description Using real-time gene expression imaging and behavioral analysis, we found that perinatal photoperiod has lasting effects on the circadian rhythms expressed by clock neurons as well as on mouse behavior, and sets the responsiveness of the biological clock to subsequent changes in photoperiod. These developmental gene x environment interactions tune circadian clock responses to subsequent seasonal photoperiods and may contribute to the influence of season on neurobehavioral disorders in humans.
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spelling pubmed-30582922011-07-01 Perinatal photoperiod imprints the circadian clock Ciarleglio, Christopher M Axley, John C Strauss, Benjamin R Gamble, Karen L McMahon, Douglas G Nat Neurosci Article Using real-time gene expression imaging and behavioral analysis, we found that perinatal photoperiod has lasting effects on the circadian rhythms expressed by clock neurons as well as on mouse behavior, and sets the responsiveness of the biological clock to subsequent changes in photoperiod. These developmental gene x environment interactions tune circadian clock responses to subsequent seasonal photoperiods and may contribute to the influence of season on neurobehavioral disorders in humans. 2010-12-05 2011-01 /pmc/articles/PMC3058292/ /pubmed/21131951 http://dx.doi.org/10.1038/nn.2699 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Ciarleglio, Christopher M
Axley, John C
Strauss, Benjamin R
Gamble, Karen L
McMahon, Douglas G
Perinatal photoperiod imprints the circadian clock
title Perinatal photoperiod imprints the circadian clock
title_full Perinatal photoperiod imprints the circadian clock
title_fullStr Perinatal photoperiod imprints the circadian clock
title_full_unstemmed Perinatal photoperiod imprints the circadian clock
title_short Perinatal photoperiod imprints the circadian clock
title_sort perinatal photoperiod imprints the circadian clock
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058292/
https://www.ncbi.nlm.nih.gov/pubmed/21131951
http://dx.doi.org/10.1038/nn.2699
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AT gamblekarenl perinatalphotoperiodimprintsthecircadianclock
AT mcmahondouglasg perinatalphotoperiodimprintsthecircadianclock

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