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Integrin α(v)β(3)-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy
PURPOSE: Gold nanoshells (NSs) have already shown great promise as photothermal actuators for cancer therapy. Integrin α(v)β(3) is a marker that is specifically and preferentially overexpressed on multiple tumor types and on angiogenic tumor neovasculature. Active targeting of NSs to integrin α(v)β(...
Autores principales: | Xie, Huan, Diagaradjane, Parmeswaran, Deorukhkar, Amit A, Goins, Beth, Bao, Ande, Phillips, William T, Wang, Zheng, Schwartz, Jon, Krishnan, Sunil |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058535/ https://www.ncbi.nlm.nih.gov/pubmed/21423588 http://dx.doi.org/10.2147/IJN.S15479 |
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