Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides

Distinguishing tumor recurrence from radiation necrosis following brain tumor therapy remains a major clinical challenge. Here we demonstrate the ability to distinguish these lesions using the amide proton transfer (APT) MRI signals of endogenous cellular proteins and peptides as an imaging biomarke...

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Detalles Bibliográficos
Autores principales: Zhou, Jinyuan, Tryggestad, Erik, Wen, Zhibo, Lal, Bachchu, Zhou, Tingting, Grossman, Rachel, Wang, Silun, Yan, Kun, Fu, De-Xue, Ford, Eric, Tyler, Betty, Blakeley, Jaishri, Laterra, John, van Zijl, Peter C.M.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058561/
https://www.ncbi.nlm.nih.gov/pubmed/21170048
http://dx.doi.org/10.1038/nm.2268

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