Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

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By triggering immunogenic cell death, some anticancer compounds, including anthracyclines and oxaliplatin, elicit tumor-specific, interferon-γ–producing CD8(+) αβ T lymphocytes (Tc1 CTLs) that are pivotal for an optimal therapeutic outcome. Here, we demonstrate that chemotherapy induces a rapid and...

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Detalles Bibliográficos
Autores principales: Ma, Yuting, Aymeric, Laetitia, Locher, Clara, Mattarollo, Stephen R., Delahaye, Nicolas F., Pereira, Pablo, Boucontet, Laurent, Apetoh, Lionel, Ghiringhelli, François, Casares, Noëlia, Lasarte, Juan José, Matsuzaki, Goro, Ikuta, Koichi, Ryffel, Bernard, Benlagha, Kamel, Tesnière, Antoine, Ibrahim, Nicolas, Déchanet-Merville, Julie, Chaput, Nathalie, Smyth, Mark J., Kroemer, Guido, Zitvogel, Laurence
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058575/
https://www.ncbi.nlm.nih.gov/pubmed/21383056
http://dx.doi.org/10.1084/jem.20100269

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