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VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses
The immunoglobulin (Ig) superfamily consists of many critical immune regulators, including the B7 family ligands and receptors. In this study, we identify a novel and structurally distinct Ig superfamily inhibitory ligand, whose extracellular domain bears homology to the B7 family ligand PD-L1. This...
Autores principales: | Wang, Li, Rubinstein, Rotem, Lines, Janet L., Wasiuk, Anna, Ahonen, Cory, Guo, Yanxia, Lu, Li-Fan, Gondek, David, Wang, Yan, Fava, Roy A., Fiser, Andras, Almo, Steve, Noelle, Randolph J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058578/ https://www.ncbi.nlm.nih.gov/pubmed/21383057 http://dx.doi.org/10.1084/jem.20100619 |
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