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Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes

The innate signaling pathways for Th2 immunity activated by inhaled antigens are not well defined. We previously identified Dectin-2 as a receptor for glycans in allergen extracts from the house dust mite Dermatophagoides farinae (Df) that mediates cysteinyl leukotriene (cys-LT) generation from pulm...

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Detalles Bibliográficos
Autores principales:	Barrett, Nora A., Rahman, Opu M., Fernandez, James M., Parsons, Matthew W., Xing, Wei, Austen, K. Frank, Kanaoka, Yoshihide
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058587/ https://www.ncbi.nlm.nih.gov/pubmed/21357742 http://dx.doi.org/10.1084/jem.20100793

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