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Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations
AIMS: Recent immunohistochemical studies observed the loss of plakoglobin (PG) from the intercalated disc (ID) as a hallmark of arrhythmogenic right ventricular cardiomyopathy (ARVC), suggesting a final common pathway for this disease. However, the underlying molecular processes are poorly understoo...
Autores principales: | Gehmlich, Katja, Syrris, Petros, Peskett, Emma, Evans, Alison, Ehler, Elisabeth, Asimaki, Angeliki, Anastasakis, Aris, Tsatsopoulou, Adalena, Vouliotis, Apostolos-Ilias, Stefanadis, Christodoulos, Saffitz, Jeffrey E., Protonotarios, Nikos, McKenna, William J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058729/ https://www.ncbi.nlm.nih.gov/pubmed/21062920 http://dx.doi.org/10.1093/cvr/cvq353 |
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