Central Nervous System (CNS) Delivery of Glucocorticoids Is Fine-Tuned by Saturable Transporters at the Blood-CNS Barriers and Nonbarrier Regions

Proper functioning of the hypothalamic-pituitary-adrenal axis depends on the ability of glucocorticoids (GCs), mainly cortisol in humans and corticosterone in rodents, to access brain targets and regulate their own secretion. Being highly lipophilic, GCs have been assumed to passively diffuse throug...

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Detalles Bibliográficos
Autores principales: Mason, Brittany L., Pariante, Carmine M., Jamel, Sara, Thomas, Sarah A.
Formato: Texto
Lenguaje:English
Publicado: Endocrine Society 2010
Materias:
Glucocorticoids-CRH-ACTH-Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058749/
https://www.ncbi.nlm.nih.gov/pubmed/20881247
http://dx.doi.org/10.1210/en.2010-0554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058749/
https://www.ncbi.nlm.nih.gov/pubmed/20881247
http://dx.doi.org/10.1210/en.2010-0554

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