Src activates Abl to augment Robo1 expression in order to promote tumor cell migration

Cell migration is an essential step in cancer invasion and metastasis. A number of orchestrated cellular events involving tyrosine kinases and signaling receptors enable cancer cells to dislodge from primary tumors and colonize elsewhere in the body. For example, activation of the Src and Abl kinase...

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Detalles Bibliográficos
Autores principales: Khusial, P. Raaj, Vadla, Bhaskar, Krishnan, Harini, Ramlall, Trudy F., Shen, Yongquan, Ichikawa, Hitoshi, Geng, Jian-Guo, Goldberg, Gary S.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058788/
https://www.ncbi.nlm.nih.gov/pubmed/21301049

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