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Human T cell leukemia virus type 1 (HTLV-1) and oncogene or oncomiR addiction?
The mechanism of HTLV-1 transformation of cells to Adult T cell leukemia (ATL) remains not fully understood. Currently, the viral Tax oncoprotein is known to be required to initiate transformation. Emerging evidence suggests that Tax is not needed to maintain the transformed ATL phenotype. Recent st...
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| Formato: | Texto |
| Lenguaje: | English |
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Impact Journals LLC
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058865/ https://www.ncbi.nlm.nih.gov/pubmed/21311101 |