Small Molecule AKAP-Protein Kinase A (PKA) Interaction Disruptors That Activate PKA Interfere with Compartmentalized cAMP Signaling in Cardiac Myocytes

A-kinase anchoring proteins (AKAPs) tether protein kinase A (PKA) and other signaling proteins to defined intracellular sites, thereby establishing compartmentalized cAMP signaling. AKAP-PKA interactions play key roles in various cellular processes, including the regulation of cardiac myocyte contra...

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Detalles Bibliográficos
Autores principales: Christian, Frank, Szaszák, Márta, Friedl, Sabine, Drewianka, Stephan, Lorenz, Dorothea, Goncalves, Andrey, Furkert, Jens, Vargas, Carolyn, Schmieder, Peter, Götz, Frank, Zühlke, Kerstin, Moutty, Marie, Göttert, Hendrikje, Joshi, Mangesh, Reif, Bernd, Haase, Hannelore, Morano, Ingo, Grossmann, Solveig, Klukovits, Anna, Verli, Judit, Gáspár, Róbert, Noack, Claudia, Bergmann, Martin, Kass, Robert, Hampel, Kornelia, Kashin, Dmitry, Genieser, Hans-Gottfried, Herberg, Friedrich W., Willoughby, Debbie, Cooper, Dermot M. F., Baillie, George S., Houslay, Miles D., von Kries, Jens Peter, Zimmermann, Bastian, Rosenthal, Walter, Klussmann, Enno
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058960/
https://www.ncbi.nlm.nih.gov/pubmed/21177871
http://dx.doi.org/10.1074/jbc.M110.160614

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