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Proprotein Convertases Process Pmel17 during Secretion
Pmel17 is a melanocyte/melanoma-specific protein that traffics to melanosomes where it forms a fibrillar matrix on which melanin gets deposited. Before being cleaved into smaller fibrillogenic fragments the protein undergoes processing by proprotein convertases, a class of serine proteases that typi...
Autores principales: | Leonhardt, Ralf M., Vigneron, Nathalie, Rahner, Christoph, Cresswell, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059051/ https://www.ncbi.nlm.nih.gov/pubmed/21247888 http://dx.doi.org/10.1074/jbc.M110.168088 |
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