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Ha-Ras stabilization mediates pro-fibrotic signals in dermal fibroblasts
BACKGROUND: Scleroderma (systemic sclerosis; SSc) is a clinically heterogeneous and often lethal acquired disorder of the connective tissue that is characterized by vascular, immune/inflammatory and fibrotic manifestations. Tissue fibrosis is the main cause of morbidity and mortality in SSc and an u...
Autores principales: | Smaldone, Silvia, Olivieri, Jacopo, Gusella, Gabriele Luca, Moroncini, Gianluca, Gabrielli, Armando, Ramirez, Francesco |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059295/ https://www.ncbi.nlm.nih.gov/pubmed/21362163 http://dx.doi.org/10.1186/1755-1536-4-8 |
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