Cargando…
Effect of Tectona grandis Linn. seeds on hair growth activity of albino mice
The seeds of Tectona grandis Linn. are traditionally acclaimed as hair tonic in the Indian system of medicine. Studies were therefore undertaken in order to evaluate petroleum ether extract of T. grandis seeds for its effect on hair growth in albino mice. The 5% and 10% extracts incorporated into si...
Autores principales: | , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059442/ https://www.ncbi.nlm.nih.gov/pubmed/21455447 http://dx.doi.org/10.4103/0974-7788.76783 |
_version_ | 1782200406605037568 |
---|---|
author | Jaybhaye, Deepali Varma, Sushikumar Gagne, Nitin bonde, Vijay Gite, Amol Bhosle, Deepak |
author_facet | Jaybhaye, Deepali Varma, Sushikumar Gagne, Nitin bonde, Vijay Gite, Amol Bhosle, Deepak |
author_sort | Jaybhaye, Deepali |
collection | PubMed |
description | The seeds of Tectona grandis Linn. are traditionally acclaimed as hair tonic in the Indian system of medicine. Studies were therefore undertaken in order to evaluate petroleum ether extract of T. grandis seeds for its effect on hair growth in albino mice. The 5% and 10% extracts incorporated into simple ointment base were applied topically on shaved denuded skin of albino mice. The time required for initiation of hair growth as well as completion of hair growth cycle was recorded. Minoxidil 2% solution was applied topically and served as positive control. The result of treatment with minoxidil 2% is 49% hair in anagenic phase. Hair growth initiation time was significantly reduced to half on treatment with the extracts compared to control animals. The treatment was successful in bringing a greater number of hair follicles (64% and 51%) in anagenic phase than standard minoxidil (49%). The results of treatment with 5% and 10% petroleum ether extracts were comparable to the positive control minoxidil. |
format | Text |
id | pubmed-3059442 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-30594422011-03-31 Effect of Tectona grandis Linn. seeds on hair growth activity of albino mice Jaybhaye, Deepali Varma, Sushikumar Gagne, Nitin bonde, Vijay Gite, Amol Bhosle, Deepak Int J Ayurveda Res Original Article The seeds of Tectona grandis Linn. are traditionally acclaimed as hair tonic in the Indian system of medicine. Studies were therefore undertaken in order to evaluate petroleum ether extract of T. grandis seeds for its effect on hair growth in albino mice. The 5% and 10% extracts incorporated into simple ointment base were applied topically on shaved denuded skin of albino mice. The time required for initiation of hair growth as well as completion of hair growth cycle was recorded. Minoxidil 2% solution was applied topically and served as positive control. The result of treatment with minoxidil 2% is 49% hair in anagenic phase. Hair growth initiation time was significantly reduced to half on treatment with the extracts compared to control animals. The treatment was successful in bringing a greater number of hair follicles (64% and 51%) in anagenic phase than standard minoxidil (49%). The results of treatment with 5% and 10% petroleum ether extracts were comparable to the positive control minoxidil. Medknow Publications & Media Pvt Ltd 2010 /pmc/articles/PMC3059442/ /pubmed/21455447 http://dx.doi.org/10.4103/0974-7788.76783 Text en Copyright: © International Journal of Ayurveda Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Jaybhaye, Deepali Varma, Sushikumar Gagne, Nitin bonde, Vijay Gite, Amol Bhosle, Deepak Effect of Tectona grandis Linn. seeds on hair growth activity of albino mice |
title | Effect of Tectona grandis Linn. seeds on hair growth activity of albino mice |
title_full | Effect of Tectona grandis Linn. seeds on hair growth activity of albino mice |
title_fullStr | Effect of Tectona grandis Linn. seeds on hair growth activity of albino mice |
title_full_unstemmed | Effect of Tectona grandis Linn. seeds on hair growth activity of albino mice |
title_short | Effect of Tectona grandis Linn. seeds on hair growth activity of albino mice |
title_sort | effect of tectona grandis linn. seeds on hair growth activity of albino mice |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059442/ https://www.ncbi.nlm.nih.gov/pubmed/21455447 http://dx.doi.org/10.4103/0974-7788.76783 |
work_keys_str_mv | AT jaybhayedeepali effectoftectonagrandislinnseedsonhairgrowthactivityofalbinomice AT varmasushikumar effectoftectonagrandislinnseedsonhairgrowthactivityofalbinomice AT gagnenitin effectoftectonagrandislinnseedsonhairgrowthactivityofalbinomice AT bondevijay effectoftectonagrandislinnseedsonhairgrowthactivityofalbinomice AT giteamol effectoftectonagrandislinnseedsonhairgrowthactivityofalbinomice AT bhosledeepak effectoftectonagrandislinnseedsonhairgrowthactivityofalbinomice |