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Evidence for how APC-C-Cdc20 changes its substrate specificity in mitosis
Progress through mitosis requires that the right protein be degraded at the right time. One ubiquitin ligase, the Anaphase Promoting Complex or Cyclosome (APC-C) targets most of the crucial mitotic regulators by changing its substrate specificity throughout mitosis. The Spindle Assembly Checkpoint (...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059483/ https://www.ncbi.nlm.nih.gov/pubmed/21336306 http://dx.doi.org/10.1038/ncb2165 |