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Enhanced Long-Term Microcircuit Plasticity in the Valproic Acid Animal Model of Autism

A single intra-peritoneal injection of valproic acid (VPA) on embryonic day (ED) 11.5 to pregnant rats has been shown to produce severe autistic-like symptoms in the offspring. Previous studies showed that the microcircuitry is hyperreactive due to hyperconnectivity of glutamatergic synapses and hyp...

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Detalles Bibliográficos
Autores principales:	Silva, Guilherme Testa, Le Bé, Jean-Vincent, Riachi, Imad, Rinaldi, Tania, Markram, Kamila, Markram, Henry
Formato:	Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2009
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059606/ https://www.ncbi.nlm.nih.gov/pubmed/21423407 http://dx.doi.org/10.3389/neuro.19.001.2009

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