Increased Cell–Cell Coupling Increases Infarct Size and Does not Decrease Incidence of Ventricular Tachycardia in Mice

Increasing connexin43 (Cx43) gap junctional conductance as a means to improve cardiac conduction has been proposed as a novel antiarrhythmic modality. Yet, transmission of molecules via gap junctions may be associated with increased infarct size. To determine whether maintaining open gap junction ch...

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Detalles Bibliográficos
Autores principales: Prestia, Kevin A., Sosunov, Eugene A., Anyukhovsky, Evgeny P., Dolmatova, Elena, Kelly, Caitlin W., Brink, Peter R., Robinson, Richard B., Rosen, Michael R., Duffy, Heather S.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059611/
https://www.ncbi.nlm.nih.gov/pubmed/21423411
http://dx.doi.org/10.3389/fphys.2011.00001

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