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Psychosocial Findings in Alcohol-Dependent Patients Before and After Three Months of Total Alcohol Abstinence

Alcohol use disorders (AUDs) may be associated with several psychological and affective disorders. It is controversial, however, if these symptoms are a cause or rather a consequence of alcohol dependence. There are few data testing simultaneously psychosocial and affective disorders before and afte...

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Autores principales: Ferrulli, Anna, Leggio, Lorenzo, Cardone, Silvia, D'Angelo, Cristina, Mirijello, Antonio, Vonghia, Luisa, Miceli, Antonio, Gasbarrini, Giovanni, Addolorato, Giovanni
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059637/
https://www.ncbi.nlm.nih.gov/pubmed/21423428
http://dx.doi.org/10.3389/fpsyt.2010.00017
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author Ferrulli, Anna
Leggio, Lorenzo
Cardone, Silvia
D'Angelo, Cristina
Mirijello, Antonio
Vonghia, Luisa
Miceli, Antonio
Gasbarrini, Giovanni
Addolorato, Giovanni
author_facet Ferrulli, Anna
Leggio, Lorenzo
Cardone, Silvia
D'Angelo, Cristina
Mirijello, Antonio
Vonghia, Luisa
Miceli, Antonio
Gasbarrini, Giovanni
Addolorato, Giovanni
author_sort Ferrulli, Anna
collection PubMed
description Alcohol use disorders (AUDs) may be associated with several psychological and affective disorders. It is controversial, however, if these symptoms are a cause or rather a consequence of alcohol dependence. There are few data testing simultaneously psychosocial and affective disorders before and after a period of alcohol abstinence. The aim of this study was to perform multiple psychometric evaluations in alcohol-dependent patients before and after 12 weeks of abstinence. Twenty-five alcohol-dependent patients were included in the study. The following psychometric tests were administered at baseline (T0) and after 12 weeks (T1): addiction severity index (ASI), brief psychiatric rating scale (BPRS), social behavior scale (SBS), Sheehan disability scale (DISS), aggression questionnaire (AQ). At T1, 16 (64%) patients were abstinent, 5 (20%) patients dropped out and 4 (16%) patients relapsed. Compared to T0, patients totally abstinent at T1 showed a significant reduction of the scores related to BPRS, BPRS-E and its subscales (except BPRS 5), ASI 1, ASI 2, ASI 3, ASI 6, ASI 7, BSM, AQ, DISS 1, DISS 2, DISS 3 (p < 0.05). No significant changes in ASI 4, ASI 5, DISS 4, and DISS 5, BPRS 5 scores were found at T1 compared to T0. The present study indicates that total alcohol abstinence improves psychometric features, such as alcohol addiction severity, psychiatric rating, social behavior, aggressiveness, and disability. Larger controlled studies are needed to confirm these findings.
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spelling pubmed-30596372011-03-21 Psychosocial Findings in Alcohol-Dependent Patients Before and After Three Months of Total Alcohol Abstinence Ferrulli, Anna Leggio, Lorenzo Cardone, Silvia D'Angelo, Cristina Mirijello, Antonio Vonghia, Luisa Miceli, Antonio Gasbarrini, Giovanni Addolorato, Giovanni Front Psychiatry Psychiatry Alcohol use disorders (AUDs) may be associated with several psychological and affective disorders. It is controversial, however, if these symptoms are a cause or rather a consequence of alcohol dependence. There are few data testing simultaneously psychosocial and affective disorders before and after a period of alcohol abstinence. The aim of this study was to perform multiple psychometric evaluations in alcohol-dependent patients before and after 12 weeks of abstinence. Twenty-five alcohol-dependent patients were included in the study. The following psychometric tests were administered at baseline (T0) and after 12 weeks (T1): addiction severity index (ASI), brief psychiatric rating scale (BPRS), social behavior scale (SBS), Sheehan disability scale (DISS), aggression questionnaire (AQ). At T1, 16 (64%) patients were abstinent, 5 (20%) patients dropped out and 4 (16%) patients relapsed. Compared to T0, patients totally abstinent at T1 showed a significant reduction of the scores related to BPRS, BPRS-E and its subscales (except BPRS 5), ASI 1, ASI 2, ASI 3, ASI 6, ASI 7, BSM, AQ, DISS 1, DISS 2, DISS 3 (p < 0.05). No significant changes in ASI 4, ASI 5, DISS 4, and DISS 5, BPRS 5 scores were found at T1 compared to T0. The present study indicates that total alcohol abstinence improves psychometric features, such as alcohol addiction severity, psychiatric rating, social behavior, aggressiveness, and disability. Larger controlled studies are needed to confirm these findings. Frontiers Research Foundation 2010-07-06 /pmc/articles/PMC3059637/ /pubmed/21423428 http://dx.doi.org/10.3389/fpsyt.2010.00017 Text en Copyright © 2010 Ferrulli, Leggio, Cardone, D'Angelo, Mirijello, Vonghia, Miceli, Gasbarrini and Addolorato. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
spellingShingle Psychiatry
Ferrulli, Anna
Leggio, Lorenzo
Cardone, Silvia
D'Angelo, Cristina
Mirijello, Antonio
Vonghia, Luisa
Miceli, Antonio
Gasbarrini, Giovanni
Addolorato, Giovanni
Psychosocial Findings in Alcohol-Dependent Patients Before and After Three Months of Total Alcohol Abstinence
title Psychosocial Findings in Alcohol-Dependent Patients Before and After Three Months of Total Alcohol Abstinence
title_full Psychosocial Findings in Alcohol-Dependent Patients Before and After Three Months of Total Alcohol Abstinence
title_fullStr Psychosocial Findings in Alcohol-Dependent Patients Before and After Three Months of Total Alcohol Abstinence
title_full_unstemmed Psychosocial Findings in Alcohol-Dependent Patients Before and After Three Months of Total Alcohol Abstinence
title_short Psychosocial Findings in Alcohol-Dependent Patients Before and After Three Months of Total Alcohol Abstinence
title_sort psychosocial findings in alcohol-dependent patients before and after three months of total alcohol abstinence
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059637/
https://www.ncbi.nlm.nih.gov/pubmed/21423428
http://dx.doi.org/10.3389/fpsyt.2010.00017
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