Matrix Metalloproteinases, Synaptic Injury, and Multiple Sclerosis

Multiple sclerosis (MS) is a disease of the central nervous system in which immune mediated damage to myelin is characteristic. For an overview of this condition and its pathophysiology, please refer to one of many excellent published reviews (Sorensen and Ransohoff, 1998; Weiner, 2009). To follow,...

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Detalles Bibliográficos
Autores principales: Szklarczyk, Arek, Conant, Katherine
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059646/
https://www.ncbi.nlm.nih.gov/pubmed/21423441
http://dx.doi.org/10.3389/fpsyt.2010.00130
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author Szklarczyk, Arek
Conant, Katherine
author_facet Szklarczyk, Arek
Conant, Katherine
author_sort Szklarczyk, Arek
collection PubMed
description Multiple sclerosis (MS) is a disease of the central nervous system in which immune mediated damage to myelin is characteristic. For an overview of this condition and its pathophysiology, please refer to one of many excellent published reviews (Sorensen and Ransohoff, 1998; Weiner, 2009). To follow, is a discussion focused on the possibility that synaptic injury occurs in at least a subset of patients, and that matrix metalloproteinases (MMPs) play a role in such.
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spelling pubmed-30596462011-03-21 Matrix Metalloproteinases, Synaptic Injury, and Multiple Sclerosis Szklarczyk, Arek Conant, Katherine Front Psychiatry Psychiatry Multiple sclerosis (MS) is a disease of the central nervous system in which immune mediated damage to myelin is characteristic. For an overview of this condition and its pathophysiology, please refer to one of many excellent published reviews (Sorensen and Ransohoff, 1998; Weiner, 2009). To follow, is a discussion focused on the possibility that synaptic injury occurs in at least a subset of patients, and that matrix metalloproteinases (MMPs) play a role in such. Frontiers Research Foundation 2010-10-05 /pmc/articles/PMC3059646/ /pubmed/21423441 http://dx.doi.org/10.3389/fpsyt.2010.00130 Text en Copyright © 2010 Szklarczyk and Conant. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
spellingShingle Psychiatry
Szklarczyk, Arek
Conant, Katherine
Matrix Metalloproteinases, Synaptic Injury, and Multiple Sclerosis
title Matrix Metalloproteinases, Synaptic Injury, and Multiple Sclerosis
title_full Matrix Metalloproteinases, Synaptic Injury, and Multiple Sclerosis
title_fullStr Matrix Metalloproteinases, Synaptic Injury, and Multiple Sclerosis
title_full_unstemmed Matrix Metalloproteinases, Synaptic Injury, and Multiple Sclerosis
title_short Matrix Metalloproteinases, Synaptic Injury, and Multiple Sclerosis
title_sort matrix metalloproteinases, synaptic injury, and multiple sclerosis
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059646/
https://www.ncbi.nlm.nih.gov/pubmed/21423441
http://dx.doi.org/10.3389/fpsyt.2010.00130
work_keys_str_mv AT szklarczykarek matrixmetalloproteinasessynapticinjuryandmultiplesclerosis
AT conantkatherine matrixmetalloproteinasessynapticinjuryandmultiplesclerosis

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