Sensing of Replication Stress and Mec1 Activation Act through Two Independent Pathways Involving the 9-1-1 Complex and DNA Polymerase ε

Following DNA damage or replication stress, budding yeast cells activate the Rad53 checkpoint kinase, promoting genome stability in these challenging conditions. The DNA damage and replication checkpoint pathways are partially overlapping, sharing several factors, but are also differentiated at vari...

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Detalles Bibliográficos
Autores principales: Puddu, Fabio, Piergiovanni, Gabriele, Plevani, Paolo, Muzi-Falconi, Marco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060063/
https://www.ncbi.nlm.nih.gov/pubmed/21436894
http://dx.doi.org/10.1371/journal.pgen.1002022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060063/
https://www.ncbi.nlm.nih.gov/pubmed/21436894
http://dx.doi.org/10.1371/journal.pgen.1002022

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