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H3K9me2/3 Binding of the MBT Domain Protein LIN-61 Is Essential for Caenorhabditis elegans Vulva Development

MBT domain proteins are involved in developmental processes and tumorigenesis. In vitro binding and mutagenesis studies have shown that individual MBT domains within clustered MBT repeat regions bind mono- and dimethylated histone lysine residues with little to no sequence specificity but discrimina...

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Detalles Bibliográficos
Autores principales: Koester-Eiserfunke, Nora, Fischle, Wolfgang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060068/
https://www.ncbi.nlm.nih.gov/pubmed/21437264
http://dx.doi.org/10.1371/journal.pgen.1002017

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