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Triplet Repeat–Derived siRNAs Enhance RNA–Mediated Toxicity in a Drosophila Model for Myotonic Dystrophy

More than 20 human neurological and neurodegenerative diseases are caused by simple DNA repeat expansions; among these, non-coding CTG repeat expansions are the basis of myotonic dystrophy (DM1). Recent work, however, has also revealed that many human genes have anti-sense transcripts, raising the p...

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Detalles Bibliográficos
Autores principales:	Yu, Zhenming, Teng, Xiuyin, Bonini, Nancy M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060073/ https://www.ncbi.nlm.nih.gov/pubmed/21437269 http://dx.doi.org/10.1371/journal.pgen.1001340

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