Oncogene Activation Induces Metabolic Transformation Resulting in Insulin-Independence in Human Breast Cancer Cells

Normal breast epithelial cells require insulin and EGF for growth in serum-free media. We previously demonstrated that over expression of breast cancer oncogenes transforms MCF10A cells to an insulin-independent phenotype. Additionally, most breast cancer cell lines are insulin-independent for growt...

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Detalles Bibliográficos
Autores principales: Bollig-Fischer, Aliccia, Dewey, T. Gregory, Ethier, Stephen P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060101/
https://www.ncbi.nlm.nih.gov/pubmed/21437235
http://dx.doi.org/10.1371/journal.pone.0017959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060101/
https://www.ncbi.nlm.nih.gov/pubmed/21437235
http://dx.doi.org/10.1371/journal.pone.0017959

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